Nagase K, Ohtsu A, Saito Y, Saito M, Ikeya S, Ishii N, Nakayama H, Hoshino E, Sugai Y, Wachi E
Department of Internal Medicine, Iwaki Kyoritsu General Hospital.
Jpn J Clin Oncol. 1991 Aug;21(4):299-305.
A long-term survivor of advanced gastric cancer with multiple metastases to the liver treated by chemotherapy is described. Chemotherapy comprising a combination of uracil and tegafur with mitomycin C achieved a complete response in the patient which lasted for approximately four years. Four years after initiation of the chemotherapy, a unique form of cancer recurrence occurred on the skin, showing infiltrative erythema. Cancer metastases developed further despite more treatment, and the patient died of generalized metastasis four years six months after the initiation of chemotherapy. It is significant that, at autopsy, no cancer cells were revealed in the primary lesion or in the liver which had been present before the initial chemotherapy.
