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[给予微量混合胆汁酸的大鼠胃上皮细胞形态计量分析及细胞周期研究]

[Studies of morphometric analysis and cell cycle of gastric epithelia of rat administered minimal mixed bile acids].

作者信息

Murata T, Wada R, Abe H, Kuwabara N, Fukuda Y

机构信息

Department of Veterinary Surgery, Yamaguchi University.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 1991 Aug;88(8):1532-8.

PMID:1942607
Abstract

The gastric epithelia of the rat after administrated with the minimal mixed bile acids and lysozyme for 9-weeks were studied using morphometric analysis and anti-Bromodeoxyuridine staining immunohistochemistry. Our results show that the atrophic changes and increased anti-BrdU antibody staining positive and mitotic cells of the pyloric glands area in the group administration only bile acids. Lysozyme inhibited bile acids activation on these changes of this area.

摘要

用形态计量分析和抗溴脱氧尿苷染色免疫组织化学方法研究了大鼠给予最低混合胆汁酸和溶菌酶9周后的胃上皮。我们的结果表明,仅给予胆汁酸组的幽门腺区出现萎缩性改变,抗BrdU抗体染色阳性细胞和有丝分裂细胞增加。溶菌酶抑制了胆汁酸对该区域这些变化的激活作用。

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[Studies of morphometric analysis and cell cycle of gastric epithelia of rat administered minimal mixed bile acids].[给予微量混合胆汁酸的大鼠胃上皮细胞形态计量分析及细胞周期研究]
Nihon Shokakibyo Gakkai Zasshi. 1991 Aug;88(8):1532-8.
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引用本文的文献

1
Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part III. Proliferation in normal, injured and diseased tissue, growth factors, differentiation, DNA replication sites and in situ hybridization.溴脱氧尿苷:生物学与医学中的一种诊断工具,第三部分。正常、损伤及患病组织中的增殖、生长因子、分化、DNA复制位点及原位杂交
Histochem J. 1996 Aug;28(8):531-75. doi: 10.1007/BF02331377.