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审查维生素C在预防和治疗普通感冒中应用的证据。

Examining the evidence for the use of vitamin C in the prophylaxis and treatment of the common cold.

作者信息

Heimer Kathryn A, Hart Ann Marie, Martin Linda Gore, Rubio-Wallace Sherrie

机构信息

Laramie Reproductive Health, Laramie, Wyoming, USA.

出版信息

J Am Acad Nurse Pract. 2009 May;21(5):295-300. doi: 10.1111/j.1745-7599.2009.00409.x.

Abstract

PURPOSE

To present a critical evaluation of the current evidence concerning the therapeutic value of vitamin C for the prophylaxis and treatment of the common cold.

DATA SOURCES

Cochrane, PubMed, Natural Standard, and the National Center for Complementary and Alternative Medicine databases were searched to identify and acquire primary research reports, literature reviews, and secondary analyses related to the clinical objective. Published clinical trials, literature reviews, meta-analyses, and systematic reviews were evaluated for evidence-based practice implications.

CONCLUSIONS

Vitamin C is frequently used for the treatment and prophylaxis of the common cold; however, no published recommendations were found in a review of the nurse practitioner literature that specifically address the efficacy of vitamin C for the common cold. Our literature review revealed that vitamin C is not effective at preventing the common cold in the general adult population; however, it is effective at preventing colds when consumed regularly by athletes training in subarctic conditions. We also found that regular vitamin C consumption may reduce the duration of cold symptoms in both adults and children, but it does not decrease the severity of cold symptoms.

IMPLICATIONS FOR PRACTICE

NPs should counsel their patients that regular vitamin C consumption may decrease the duration of cold symptoms, but does not affect symptom severity or act as a prophylaxis.

摘要

目的

对当前有关维生素C预防和治疗普通感冒的治疗价值的证据进行批判性评估。

数据来源

检索Cochrane、PubMed、自然标准数据库和国家补充与替代医学中心数据库,以识别和获取与临床目标相关的原始研究报告、文献综述和二次分析。对已发表的临床试验、文献综述、荟萃分析和系统评价进行评估,以了解其对循证实践的影响。

结论

维生素C常用于治疗和预防普通感冒;然而,在对执业护士文献的综述中,未发现专门针对维生素C治疗普通感冒疗效的已发表建议。我们的文献综述显示,维生素C对一般成年人群预防普通感冒无效;然而,在亚北极条件下训练的运动员经常服用时,它对预防感冒有效。我们还发现,经常服用维生素C可能会缩短成人和儿童感冒症状的持续时间,但不会减轻感冒症状的严重程度。

对实践的启示

执业护士应告知患者,经常服用维生素C可能会缩短感冒症状的持续时间,但不会影响症状严重程度,也不能起到预防作用。

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