Schmittdiel Julie A, Uratsu Connie S, Fireman Bruce H, Selby Joe V
Division of Research, Kaiser Permanente Medical Care Program, Northern California, 2000 Broadway, Oakland, CA 94612, USA.
Am J Manag Care. 2009 May;15(5):295-301.
To evaluate the effectiveness of the diabetes care management (CM) program in Kaiser Permanente Northern California (KPNC) by determining the proportion of enrollees that met program entry criteria and by comparing intermediate outcomes trajectories of enrollees versus similar patients who did not receive CM.
Observational study with propensity score matching of CM patients to control subjects.
Care management program entry criteria were assessed for 179,249 adult patients with diabetes mellitus in 2003 and were compared between CM and non-CM patients in that year. Propensity score matching was used to match CM patients with comparable non-CM controls. Preprogram and postprogram glycosylated hemoglobin (A1C), low-density lipoprotein cholesterol (LDL-C), and systolic blood pressure levels, as well as medication adherence, and treatment intensification rates of CM patients, were compared for enrollees versus controls.
Sixteen percent of CM patients were ineligible by program entry criteria. Small but statistically significant differences in A1C and LDL-C levels favoring CM patients were observed during 15 months of postprogram follow-up. Care management patients were more likely to receive treatment intensification for poorly controlled hyperglycemia, hyperlipidemia, and hypertension. Improvements in all 3 cardiovascular risk factor levels were observed for all KPNC patients with diabetes regardless of CM participation.
Eligibility guidelines for diabetes CM were not strictly adhered to in this program. Nevertheless, in a population with improving risk factor control, patients entering CM experienced slightly greater improvement.
通过确定符合项目纳入标准的参保者比例,并比较参保者与未接受糖尿病护理管理(CM)的类似患者的中间结局轨迹,评估北加利福尼亚凯撒医疗集团(KPNC)的糖尿病护理管理项目的有效性。
对CM患者与对照对象进行倾向得分匹配的观察性研究。
评估了2003年179249例成年糖尿病患者的护理管理项目纳入标准,并比较了当年CM患者与非CM患者的情况。采用倾向得分匹配法将CM患者与可比的非CM对照进行匹配。比较了参保者与对照在项目前和项目后糖化血红蛋白(A1C)、低密度脂蛋白胆固醇(LDL-C)和收缩压水平,以及CM患者的药物依从性和治疗强化率。
16%的CM患者不符合项目纳入标准。在项目后15个月的随访中,观察到A1C和LDL-C水平存在虽小但有统计学意义的差异,有利于CM患者。护理管理患者更有可能因血糖控制不佳、高脂血症和高血压而接受强化治疗。无论是否参与CM,所有KPNC糖尿病患者的所有3种心血管危险因素水平均有改善。
该项目未严格遵守糖尿病CM的资格指南。然而,在危险因素控制有所改善的人群中,进入CM的患者改善幅度略大。