Furuhashi N, Abe T, Suzuki M, Yamaya Y, Takahashi K, Hoshiai H, Wada Y
Tohoku J Exp Med. 1977 Apr;121(4):315-9. doi: 10.1620/tjem.121.315.
In order to quantify the changes of feed-back effect of estrogen on the release of pituitary gonadotropin which is regulated by the hypothalamic-pituitary-ovarian system, the responses of LH and FSH to the intravenous infusion of 20 mg of conjugated estrogen were studied in 49 post-menopausal and 20 castrated women. In the group of women within 1 year after menopause, serum LH levels were elevated following the infusion of the conjugated estrogen. The responses of serum LH and FSH levels were different between post-menopausal and castrated women. The data indicated that the difference between the two groups was probably due to the difference of secrection patterns of the gonadotropins in post-menopausal and castrated women.
为了量化雌激素对由下丘脑-垂体-卵巢系统调节的垂体促性腺激素释放的反馈作用变化，对49名绝经后妇女和20名去势妇女静脉输注20毫克结合雌激素后促黄体生成素（LH）和促卵泡生成素（FSH）的反应进行了研究。在绝经后1年内的女性组中，输注结合雌激素后血清LH水平升高。绝经后妇女和去势妇女血清LH和FSH水平的反应不同。数据表明，两组之间的差异可能是由于绝经后妇女和去势妇女促性腺激素分泌模式的差异。
