Neonatal Intensive Care Unit (NICU), Department of Paediatrics, Hospital Fernando Fonseca, IC 19. 2720-276 Amadora, Portugal.
Eur J Pediatr. 2010 Jan;169(1):99-105. doi: 10.1007/s00431-009-0995-z. Epub 2009 May 13.
The aim of this paper was to study the weight gain in very-low-birthweight (VLBW) infants by adopting earlier and higher intake of proteins and earlier intake of lipids. We studied 28 VLBW infants admitted to Neonatal Intensive Care Unit during the year 2004 (group 1) and 18 during the first semester of 2006 (group 2). Dietary intakes for group 1 were: 1 g kg(-1) day(-1) of proteins started at postnatal day 2 (P2) and 0.5-1 g kg(-1) day(-1) of lipids at P3; for group 2, 1-1.5 g kg(-1) day(-1) of proteins and 0.5-1 g kg(-1) day(-1) of lipids, both started at P1. Caloric intake was significantly higher in group 2 (p < 0.05), whereas cumulative nutritional deficit was higher in group 1 (p < or = 0.01). Weight z scores were significantly lower at discharge comparing with z scores at birth for each group (p < or = 0.01), with no differences between the two groups. Despite a higher protein intake which resulted in a lower nutritional deficit, the weight z score did not improve significantly at discharge.
本文旨在通过更早、更高地摄入蛋白质和更早地摄入脂肪来研究极低出生体重(VLBW)婴儿的体重增加情况。我们研究了 2004 年(第 1 组)和 2006 年上半年(第 2 组)入住新生儿重症监护病房的 28 名 VLBW 婴儿。第 1 组的饮食摄入量为:生后第 2 天(P2)开始摄入 1 g/kg/天的蛋白质,P3 时开始摄入 0.5-1 g/kg/天的脂肪;第 2 组在 P1 时开始摄入 1-1.5 g/kg/天的蛋白质和 0.5-1 g/kg/天的脂肪。第 2 组的热量摄入量明显高于第 1 组(p<0.05),而第 1 组的累积营养不足量更高(p<0.01)。与出生时的 z 评分相比,两组在出院时的 z 评分均显著降低(p<0.01),但两组之间无差异。尽管蛋白质摄入量较高,导致营养不足量较低,但出院时体重 z 评分并未显著改善。