Department of Mining, Metallurgical and Materials Engineering, Laval University, Québec City, Quebec, G1V 0A6 Canada.
J Biomed Mater Res A. 2010 Apr;93(1):1-11. doi: 10.1002/jbm.a.32224.
Designing materials having suitable mechanical properties and targeted degradation behavior is the key for the development of biodegradable materials for medical applications, including stents. A series of Fe-Mn alloys was developed with the objective to obtain mechanical properties similar to those of stainless steel 316L and degradation behavior more suited than pure iron. Four alloys with Mn content ranging between 20 and 35 wt % were compared in this study. Their microstructure, mechanical properties, magnetic properties as well as degradation behavior were carefully investigated. Results show that their microstructure is mainly composed of gamma phase with the appearance of epsilon phase in alloys having a lower Mn content. The yield strength and elongation of alloys was comprised between 234 MPa and 32% for Fe-35%Mn alloy to 421 MPa and 7.5% for the Fe-20%Mn alloy. All alloys show similar magnetic susceptibility ( approximately 1.8 x 10(-7) m(3)/kg) in the quenched condition. This magnetic susceptibility remains constant after plastic deformation for all the tested alloys except for the Fe-20%Mn alloy. The corrosion rate was higher than pure iron. Among the alloys studied in this work, the Fe-35%Mn alloy shows mechanical properties and degradation behavior closely approaching those required for biodegradable stents application.
设计具有合适机械性能和目标降解行为的材料是开发用于医疗应用的可生物降解材料（包括支架）的关键。本研究开发了一系列 Fe-Mn 合金，旨在获得与不锈钢 316L 相似的机械性能和比纯铁更适合的降解行为。本研究比较了四种 Mn 含量在 20 至 35wt%之间的合金。仔细研究了它们的微观结构、机械性能、磁性和降解行为。结果表明，它们的微观结构主要由伽马相组成，较低 Mn 含量的合金中出现了epsilon 相。Fe-35%Mn 合金的屈服强度和伸长率在 234MPa 和 32%之间，Fe-20%Mn 合金的屈服强度和伸长率在 421MPa 和 7.5%之间。所有合金在淬火状态下的磁导率相似（约为 1.8x10(-7)m(3)/kg）。除了 Fe-20%Mn 合金外，所有测试合金的塑性变形后磁导率均保持不变。腐蚀速率高于纯铁。在本工作研究的合金中，Fe-35%Mn 合金的机械性能和降解行为与可生物降解支架应用所需的性能非常接近。
