Bollo Robert J, Carlson Chad, Schevon Catherine, Wisoff Jeffrey H, Devinsky Orrin, Weiner Howard L
Department of Neurosurgery, Comprehensive Epilepsy Center, NYU Langone Medical Center and New York University School of Medicine, New York, NY 10016, USA.
Pediatr Neurosurg. 2009;45(3):175-80. doi: 10.1159/000218199. Epub 2009 May 14.
We present our technique for extraoperative functional mapping in awake children with supratentorial tumors near eloquent cortex. This technique may help optimize tumor resection and/or the functional outcome, especially when an awake craniotomy is not possible or in the setting of coincident seizures. After subdural electrode implantation, extraoperative functional mapping and seizure focus mapping were performed, followed by staged tumor resection. Gross total resection was achieved in 6 patients and subtotal resection in 2. No complications due to electrode placement or invasive monitoring were observed. Staged resection of pediatric brain tumors near the eloquent cortex appears safe, allows functional mapping in awake patients, and may assist in decisions between maximal tumor resection and optimal functional outcome.
我们展示了我们在清醒的患有幕上靠近功能区皮层肿瘤的儿童中进行术中功能图谱绘制的技术。该技术可能有助于优化肿瘤切除和/或功能结果,特别是在无法进行清醒开颅手术或合并癫痫发作的情况下。在硬膜下电极植入后,进行术中功能图谱绘制和癫痫灶定位,随后分阶段进行肿瘤切除。6例患者实现了全切除,2例患者实现了次全切除。未观察到因电极放置或侵入性监测导致的并发症。对于幕上靠近功能区皮层的小儿脑肿瘤,分阶段切除似乎是安全的,能够在清醒患者中进行功能图谱绘制,并且可能有助于在最大程度肿瘤切除和最佳功能结果之间做出决策。