Znati K, Daoudi A, Chbani L, Elfatemi H, Harmouch T, Bouteyeb F, Amarti A
Laboratoire d'anatomie pathologique, hôpital El-Ghassani, CHU Hassan-II, Fès, Maroc.
Ann Chir Plast Esthet. 2009 Dec;54(6):600-2. doi: 10.1016/j.anplas.2009.02.005. Epub 2009 May 13.
Intravascular papillary endothelial hyperplasia (IPEH) is an unusual, benign, non-neoplasic, vascular lesion characterized histologically by papillary fronds lined by proliferating endothelium. This lesion has the propensity to occur in the skin and the subcutis. Many histological features are similar to those of low-grade angiosarcoma, a common, but more serious condition. Clinical and histological differentiation is important to avoid overtreatment of this benign lesion. We report a case of cutaneous IPEH in the ankle of a 30-year-old girl, which was successfully treated by excision. The pathologic findings, differential diagnosis and a review of recent literature are discussed.
血管内乳头状内皮增生(IPEH)是一种罕见的良性非肿瘤性血管病变,组织学特征为增生的内皮细胞排列成乳头状叶。该病变易发生于皮肤和皮下组织。许多组织学特征与低级别血管肉瘤相似,后者较为常见但病情更严重。临床和组织学鉴别对于避免对这种良性病变过度治疗很重要。我们报告一例30岁女性踝部皮肤IPEH病例,通过切除成功治愈。文中讨论了病理结果、鉴别诊断及近期文献回顾。