Ou Yen-Chuan, Yang Chi-Rei, Wang John, Cheng Chen-Li, Patel Vipul R
Division of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
Anticancer Res. 2009 May;29(5):1637-42.
To compare perioperative outcomes between patients undergoing robotic-assisted laparoscopic radical prostatectomy (RALP) and patients undergoing retropubic radical prostatectomy (RRP) performed by a single surgeon in Taiwan.
This study was a retrospective review of 30 consecutive patients who underwent RRP and 30 initial patients who underwent RALP. The preoperative parameters, operation parameters (operative time, vesicourethral anastomosis time, blood loss, transfusion and complication rates) and postoperative parameters (post-operative stay, catheter duration, cystography received, continence rate, sexual function and histopathologic factors) were evaluated.
Preoperative clinical parameters were similar between groups. Vesicourethral anastomosis time was shorter in RRP group than in RALP group. RRP had higher incidence of bilateral pelvic lymph node dissection than RALP (100% vs. 73.3%), but lower incidence of neurovascular bundle preservation (6.7% vs. 53.3%). Significant differences were found in blood loss (RALP 314 mL vs. RRP 912 mL) and transfusion rates (RALP 13.3% vs. RRP 60%) between groups. A statistically significant difference was found in incidence of cystograms performed between RRP and RALP groups (93.3% vs. 43.3%) before removing urethral catheter. Positive surgical margin was 20% in RRP group vs. 50% in RALP group, demonstrating statistical significance. Shorter catheterization duration and postoperative stays were found with RALP. Three-month continence rate was higher in RALP patients than in RRP patients (76.7% vs. 36.7%, p=0.04).
RALP is minimally invasive with less blood loss and lower transfusion rates than RRP. RALP had greater incidence of neurovascular bundle preservation and faster convalescence than RRP.
比较在台湾由单一外科医生实施的机器人辅助腹腔镜根治性前列腺切除术(RALP)患者与耻骨后根治性前列腺切除术(RRP)患者的围手术期结局。
本研究对30例连续接受RRP的患者和30例初始接受RALP的患者进行回顾性分析。评估术前参数、手术参数(手术时间、膀胱尿道吻合时间、失血量、输血及并发症发生率)和术后参数(术后住院时间、导尿管留置时间、接受膀胱造影检查情况、控尿率、性功能及组织病理学因素)。
两组术前临床参数相似。RRP组膀胱尿道吻合时间短于RALP组。RRP组双侧盆腔淋巴结清扫发生率高于RALP组(100%对73.3%),但保留神经血管束的发生率低于RALP组(6.7%对53.3%)。两组间失血量(RALP组314 mL对RRP组912 mL)和输血率(RALP组13.3%对RRP组60%)存在显著差异。在拔除尿道导尿管前,RRP组和RALP组膀胱造影检查发生率存在统计学显著差异(93.3%对43.3%)。RRP组手术切缘阳性率为20%,RALP组为50%,具有统计学意义。RALP组导尿管留置时间和术后住院时间较短。RALP患者3个月控尿率高于RRP患者(76.7%对36.7%,p = 0.04)。
RALP具有微创性,与RRP相比失血量更少、输血率更低。RALP保留神经血管束的发生率高于RRP,康复更快。