Yu X N, Lau J T F, Mak W W S, Cheng Y M, Lv Y H, Zhang J X
Centre for Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, PRC.
AIDS Care. 2009 May;21(5):645-54. doi: 10.1080/09540120802459770.
A random sample of 271 people living with HIV (PLWH) who were former plasma/blood donors and a convenience sample of 67 HIV negative villagers were anonymously interviewed. Compared with the non-PLWH, PLWH reported higher prevalence of symptoms of depression (adjusted OR = 2.53, p=0.001), anxiety (adjusted OR = 1.85, p=0.04), and stress (adjusted OR = 1.77, p=0.06). Of the PLWH respondents, 81.7% received Highly Active Antiretroviral Therapy (HAART); 32.1% of whom reported some side effects. Respectively 13.7%, 37.4%, and 38.4% PLWH perceived discrimination from their family members, relatives/friends, and neighbors. Absence of HAART, poor physical function, perceived discrimination from relatives and friends, and low level of resilience were associated with depression (stepwise regression; beta = - 0.28-0.17, R-square = 0.22), anxiety and stress (R-square = 0.32 and 0.16, respectively). The majority of respondents (70.1%) desired group intervention as a means for providing psychological support services. Relevant programs should both remove risk factors (e.g., absence of medical treatment, HIV-related discrimination) and promote protective factors (e.g., resilience). Support group is one of the potentially useful approaches to provide psychological support services.
对271名曾是血浆/血液捐献者的HIV感染者（PLWH）进行随机抽样，并对67名HIV阴性村民进行便利抽样，进行匿名访谈。与非PLWH相比，PLWH报告的抑郁症状患病率更高（调整后的OR = 2.53，p = 0.001）、焦虑（调整后的OR = 1.85，p = 0.04）和压力（调整后的OR = 1.77，p = 0.06）。在PLWH受访者中，81.7%接受了高效抗逆转录病毒疗法（HAART）；其中32.1%报告有一些副作用。分别有13.7%、37.4%和38.4%的PLWH感到受到家人、亲戚/朋友和邻居的歧视。未接受HAART、身体功能差、感到受到亲戚和朋友的歧视以及恢复力水平低与抑郁相关（逐步回归；β = -0.28 - 0.17，R方 = 0.22）、焦虑和压力（R方分别为0.32和0.16）。大多数受访者（70.1%）希望通过团体干预来提供心理支持服务。相关项目应既消除风险因素（如未接受治疗、与HIV相关的歧视），又促进保护因素（如恢复力）。支持小组是提供心理支持服务的潜在有用方法之一。
