Hansel Christian
Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Neuron. 2009 May 14;62(3):308-9. doi: 10.1016/j.neuron.2009.04.020.
Climbing fiber responses in cerebellar Purkinje cells are described as being invariant. In this issue of Neuron, Mathy et al. show that the complex spike waveform changes with the number of spikes in a climbing fiber burst, which depends on the phase of olivary oscillations. In turn, different complex spike profiles affect synaptic plasticity at parallel fiber synapses. Thus, information on inferior olive oscillation states is reflected in both the complex spike waveform and the parallel fiber input gain.
小脑浦肯野细胞中的攀缘纤维反应被描述为是不变的。在本期《神经元》杂志中，马西等人表明，复合峰电位波形会随着攀缘纤维爆发中的峰电位数量而变化，这取决于橄榄体振荡的相位。反过来，不同的复合峰电位特征会影响平行纤维突触处的突触可塑性。因此，关于下橄榄体振荡状态的信息会反映在复合峰电位波形和平行纤维输入增益中。
