Kuzyk Anton, Laitinen Kimmo T, Törmä Päivi
Nanoscience Center, Department of Physics, University of Jyväskylä, Finland.
Nanotechnology. 2009 Jun 10;20(23):235305. doi: 10.1088/0957-4484/20/23/235305. Epub 2009 May 18.
We describe two general approaches to the utilization of DNA origami structures for the assembly of materials. In one approach, DNA origami is used as a prefabricated template for subsequent assembly of materials. In the other, materials are assembled simultaneously with the DNA origami, i.e. the DNA origami technique is used to drive the assembly of materials. Fabrication of complex protein structures is demonstrated by these two approaches. The latter approach has the potential to be extended to the assembly of multiple materials with single attachment chemistry.
我们描述了两种利用DNA折纸结构进行材料组装的一般方法。一种方法是,将DNA折纸用作后续材料组装的预制模板。另一种方法是,材料与DNA折纸同时组装,即利用DNA折纸技术驱动材料的组装。通过这两种方法展示了复杂蛋白质结构的制造。后一种方法有可能扩展到使用单一连接化学方法组装多种材料。