Lunardi P, Missori P, Di Lorenzo N, Fortuna A
Department of Neurological Sciences, University La Sapienza, Rome, Italy.
Neurosurgery. 1991 Oct;29(4):515-7; discussion 517-8.
We report the long-term outcome of surgery for cerebral hydatid cyst in 12 children. In only one child, who had been operated on for cardiac hydatidosis a year earlier, was the brain cyst known to be secondary. Of the 12 children, 10 had a single cyst and 2 had multiple cysts. Five single cysts were removed intact by "hydatid birth," two cysts--one single and one multiple--were removed after puncture and aspiration of the cyst fluid, and the other five--four single and one multiple--were accidentally ruptured in the course of the operation. One patient died of infection of the residual space, 2 died of intracranial recurrence of the parasite (7 and 22 months later, respectively), and one, the child with secondary cerebral echinococcosis, died 6 years later of systemic echinococcosis. Eight patients who had a mean follow-up of 28 years are still living and enjoy very good health, both general and neurological. This long-term follow-up with such good results confirms the usually primary character of cerebral hydatid disease, at least in children. The combination of patent ductus arteriosus and ingestion of unboiled animals' milk might well explain how primary cerebral hydatid disease develops in children.
我们报告了12例儿童脑包虫囊肿手术的长期结果。仅1例儿童的脑囊肿为继发性,该患儿一年前曾接受心脏包虫病手术。12例儿童中,10例有单个囊肿,2例有多个囊肿。5个单个囊肿通过“包虫娩出法”完整切除,2个囊肿(1个单个囊肿和1个多个囊肿)在穿刺抽吸囊液后切除,另外5个囊肿(4个单个囊肿和1个多个囊肿)在手术过程中意外破裂。1例患者死于残留腔隙感染,2例死于寄生虫颅内复发(分别在7个月和22个月后),1例继发性脑包虫病患儿6年后死于全身性包虫病。8例患者平均随访28年,仍然健在,全身和神经系统健康状况良好。如此良好结果的长期随访证实了脑包虫病通常为原发性,至少在儿童中是这样。动脉导管未闭与饮用未煮沸的动物奶相结合很可能解释了儿童原发性脑包虫病的发病机制。