衰老抑制剂：细胞衰老（过度激活）及其药理学减缓
Aging-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration.
作者信息
Blagosklonny Mikhail V
机构信息
Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
出版信息
Cell Cycle. 2009 Jun 15;8(12):1883-7. doi: 10.4161/cc.8.12.8815. Epub 2009 Jun 21.
PMID:19448395
Abstract
Here I overview the accompanying three reports on suppression of cellular senescence with inhibitors of mTOR, PI-3K and MEK. How can growth inhibitors suppress senescence? May these aging-suppressants decelerate organismal aging? To answer these questions, we need to reconsider the meaning of aging.
摘要
在此，我概述了随附的三篇关于用mTOR、PI - 3K和MEK抑制剂抑制细胞衰老的报告。生长抑制剂如何抑制衰老？这些衰老抑制剂能否减缓机体衰老？为了回答这些问题，我们需要重新思考衰老的意义。
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