大剂量口服巴氯芬：多发性硬化症患者的经验

High-dose oral baclofen: experience in patients with multiple sclerosis.

作者信息

Smith C R, LaRocca N G, Giesser B S, Scheinberg L C

机构信息

Medical Rehabilitation Research and Training Center for Multiple Sclerosis, Albert Einstein College of Medicine, Bronx, NY 10461.

出版信息

Neurology. 1991 Nov;41(11):1829-31. doi: 10.1212/wnl.41.11.1829.

DOI:10.1212/wnl.41.11.1829

PMID:1944915

Abstract

We reviewed a 10% random sample of charts from an outpatient clinic for multiple sclerosis to determine the frequency with which baclofen was prescribed for spasticity in high doses (greater than 80 mg/d). About 20% of patients had taken high-dose baclofen, and 15% were still receiving a high dose. Taking a high dose was not associated with discontinuing treatment.

摘要

我们回顾了一家多发性硬化症门诊诊所10%的病历随机样本，以确定高剂量（大于80毫克/天）巴氯芬用于治疗痉挛的频率。约20%的患者服用过高剂量巴氯芬，15%的患者仍在接受高剂量治疗。服用高剂量与停药无关。