Facultad de Ciencias Exactas, Centro de Investigaciones del Medio Ambiente-CIMA, Universidad Nacional de La Plata (CICPBA-CONICET), 47 y 115; (1900)-La Plata, Argentina.
Environ Toxicol. 2010 Aug;25(4):339-49. doi: 10.1002/tox.20504.
Volatile organic compounds (VOCs), which play an important part indoors and outdoors, comprise differing compound groups such as n-alkanes, cycloalkanes, aromatic and chlorinated hydrocarbons and terpenes. In the current study, samples were analyzed from indoor (schools and houses, n = 92) and outdoor (n = 33) air in urban, industrial, semirural and residential areas from the region of La Plata (Argentine) to consider VOC exposure in different types of environments. VOCs were sampled for 1 month during winter for 3 years, with passive 3M monitors. Samples were extracted with CS(2) and analyzed by GC/MS detectors. The results show significant differences in concentration and distribution between indoor and outdoor samples, depending on the study area. Most VOCs predominantly originated indoors in urban, semirural and residential areas, whereas an important outdoor influence in the industrial area was observed. In all areas alkanes and aromatic compounds dominated, even though a different chemical distribution was seen. Traffic burden was determined as the major source of outdoor VOC with a benzene/toluene ratio close to 0.5. Indoors, C9-C11 alkanes, toluene and xylenes dominated, caused by human activities. In contrast, in the industrial area higher concentrations of hexane, heptane and benzene occurred outdoors and affected the indoor air significantly. The lifetime cancer risk (LCR) associated to the benzene exposure was calculated for children from the different study areas. For all groups the study showed a LCR value greater than 1 x 10(-6) related to the benzene exposure indoors as well outdoors. A value two magnitudes higher was detected indoors in the industrial area, what demonstrates the high risk for children living in this area of La Plata.
挥发性有机化合物（VOCs）在室内和室外都发挥着重要作用，它们由不同的化合物组成，如正烷烃、环烷烃、芳香烃和氯化烃以及萜烯。在本研究中，我们分析了来自布宜诺斯艾利斯地区城市、工业、半农村和居民区的室内（学校和房屋，n=92）和室外（n=33）空气样本，以考虑不同环境中的 VOC 暴露情况。在 3 年的冬季期间，使用被动式 3M 监测器采集了 1 个月的 VOC 样本。用 CS(2)提取样品，并用 GC/MS 检测器进行分析。结果表明，室内和室外样本的浓度和分布存在显著差异，这取决于研究区域。在城市、半农村和居民区，大多数 VOC 主要来源于室内，而在工业区则观察到重要的室外影响。在所有地区，烷烃和芳香族化合物都占主导地位，尽管化学分布不同。交通负荷被确定为户外 VOC 的主要来源，苯/甲苯比接近 0.5。在室内，C9-C11 烷烃、甲苯和二甲苯占主导地位，这是由人类活动引起的。相比之下，在工业区，室外空气中存在更高浓度的己烷、庚烷和苯，这对室内空气有显著影响。我们还计算了不同研究区域儿童接触苯的终生癌症风险（LCR）。对于所有群体，研究表明，室内和室外苯暴露的 LCR 值都大于 1x10(-6)，这表明生活在拉普拉塔工业区的儿童面临高风险。
