Arpesani A, Giorgetti P L, Giordanengo F, Miani S, Rampoldi V, Franch L
Istituto di Chirurgia Generale e Cardiovascolare, Università di Milano.
Minerva Cardioangiol. 1991 Apr;39(4):135-40.
The paper reviews 2014 cases of aneurysm of the abdominal aorta treated over the past 10 years at the Institute of General and Cardiovascular Surgery of the University of Milan directed by Prof. Ugo Ruberti, and analyses 38 which showed inflammatory characteristics. In spite of the low frequency of this type of aneurysm (1.8%), preoperative diagnosis is important since surgery entails greater technical difficulties than surgery for an atherosclerotic aneurysm of the abdominal aorta. In this respect the study of preoperative ESR and white blood cell levels is important: the review showed an increased ESR in 71% of cases in which the aneurysm was clearly inflammatory (a percentage which was twice that found in patients with atherosclerotic aneurysms) and increased white blood cells in 32% of cases compared to 2.6% in atherosclerotic aneurysms. Contrary to previous reports, CAT and abdominal echography were not particularly important. However, in those cases where the aneurysm was thought to be inflammatory on the basis of these findings, the Authors chose to operate once the diagnosis had been made without waiting for steroid therapy to reduce the extent of inflammation due to the well-known risk of rupture and the controversial efficacy of medical therapy.
本文回顾了过去10年在米兰大学普通与心血管外科研究所由乌戈·鲁贝蒂教授指导下治疗的2014例腹主动脉瘤病例,并分析了其中38例具有炎症特征的病例。尽管这种类型的动脉瘤发生率较低(1.8%),但术前诊断很重要,因为与腹主动脉粥样硬化性动脉瘤手术相比,此类手术技术难度更大。在这方面,术前血沉(ESR)和白细胞水平的研究很重要:该综述显示,在动脉瘤明显为炎症性的病例中,71%的患者血沉升高(这一比例是粥样硬化性动脉瘤患者的两倍),32%的病例白细胞增多,而粥样硬化性动脉瘤患者中这一比例为2.6%。与之前的报道相反,计算机断层扫描(CAT)和腹部超声检查并非特别重要。然而,基于这些发现被认为是炎症性动脉瘤的病例,作者们选择一旦确诊就进行手术,而不是等待类固醇治疗来减轻炎症程度,因为众所周知的破裂风险以及药物治疗效果存在争议。