植物性食物来源的血管紧张素I转换酶抑制肽。

Plant food-derived Angiotensin I converting enzyme inhibitory peptides.

作者信息

Guang Cuie, Phillips Robert D

机构信息

Department of Food Science and Technology, University of Georgia, Griffin, Georgia 30223-1797, USA.

出版信息

J Agric Food Chem. 2009 Jun 24;57(12):5113-20. doi: 10.1021/jf900494d.

DOI:10.1021/jf900494d

PMID:19449887

Abstract

Hypertension is one of the most common worldwide diseases that afflict humans. Angiotensin I converting enzyme (ACE) catalyzes the formation of vasoconstrictor, angiotensin II, and the inactivation of vasodilator, bradykinin. The influences of ACE on blood pressure make it an ideal target clinically and nutritionally in the treatment of hypertension. A number of animal food-derived peptides have been reviewed about their in vitro and in vivo ACE inhibitory activities. The aim of this review is to discuss the plant food-derived angiotensin I converting enzyme (ACE) inhibitory peptides from sources, production, purification, and structure to in vitro and in vivo activities.

摘要

高血压是全球最常见的困扰人类的疾病之一。血管紧张素I转换酶（ACE）催化血管收缩剂血管紧张素II的形成，并使血管舒张剂缓激肽失活。ACE对血压的影响使其成为临床上和营养上治疗高血压的理想靶点。已经对许多动物源性食品肽的体外和体内ACE抑制活性进行了综述。本综述的目的是讨论植物源性食品中血管紧张素I转换酶（ACE）抑制肽，从来源、生产、纯化、结构到体外和体内活性。