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[Aqueous humor concentration of norfloxacin following local administration].

作者信息

Behrens-Baumann W

机构信息

Abteilung Augenheilkunde, Universität, Göttingen, BRD.

出版信息

Ophthalmologica. 1991;202(4):213-6. doi: 10.1159/000310204.

DOI:10.1159/000310204
PMID:1945302
Abstract

The Aqueous humor concentration of norfloxacin was measured following topical administration in 20 eyes. The substance was applied at different time intervals. Nineteen samples obtained prior to cataract extraction had mean concentrations between 0.014 and 0.105 microgram/ml. These concentrations are under the MIC90 of most germs. One eye with minimal congestion due to a neovascular glaucoma, however, had a concentration of 0.206 microgram/ml.

摘要

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Ocular penetration of topical ciprofloxacin and norfloxacin drops and their effect upon eyelid flora.局部用环丙沙星和诺氟沙星滴眼液的眼部穿透性及其对眼睑菌群的影响。
Br J Ophthalmol. 1994 Jul;78(7):546-8. doi: 10.1136/bjo.78.7.546.