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使用BRB-ArrayTools分析基因表达数据。

Analysis of gene expression data using BRB-ArrayTools.

作者信息

Simon Richard, Lam Amy, Li Ming-Chung, Ngan Michael, Menenzes Supriya, Zhao Yingdong

机构信息

Biometric Research Branch, National Cancer Institute, Bethesda, MD 20892-7434, USA.

出版信息

Cancer Inform. 2007 Feb 4;3:11-7.

Abstract

BRB-ArrayTools is an integrated software system for the comprehensive analysis of DNA microarray experiments. It was developed by professional biostatisticians experienced in the design and analysis of DNA microarray studies and incorporates methods developed by leading statistical laboratories. The software is designed for use by biomedical scientists who wish to have access to state-of-the-art statistical methods for the analysis of gene expression data and to receive training in the statistical analysis of high dimensional data. The software provides the most extensive set of tools available for predictive classifier development and complete cross-validation. It offers extensive links to genomic websites for gene annotation and analysis tools for pathway analysis. An archive of over 100 datasets of published microarray data with associated clinical data is provided and BRB-ArrayTools automatically imports data from the Gene Expression Omnibus public archive at the National Center for Biotechnology Information.

摘要

BRB-ArrayTools是一个用于DNA微阵列实验综合分析的集成软件系统。它由在DNA微阵列研究设计和分析方面经验丰富的专业生物统计学家开发,并整合了顶尖统计实验室开发的方法。该软件供希望使用最先进统计方法分析基因表达数据并接受高维数据统计分析培训的生物医学科学家使用。该软件提供了用于预测分类器开发和完整交叉验证的最广泛工具集。它提供到基因组网站的广泛链接,用于基因注释以及通路分析的分析工具。提供了一个包含100多个已发表微阵列数据及相关临床数据的数据集存档,并且BRB-ArrayTools会自动从美国国立生物技术信息中心的基因表达综合公共存档中导入数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d2/2675854/8ba05a6f439f/CIN-03-11-g001.jpg

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