Lindley Pam, Pestano Cecile R, Gargiulo Kathryn
Research Concepts, Memorial Hermann-Memorial City Hospital, Houston, Texas, USA.
J Adv Nurs. 2009 Jul;65(7):1370-80. doi: 10.1111/j.1365-2648.2009.04991.x. Epub 2009 May 9.
To compare the effect of fentanyl iontophoretic transdermal system and morphine intravenous patient-controlled analgesia on the time-efficiency and convenience of postoperative patient care.
Intravenous patient-controlled analgesia with morphine is effectively used to manage postoperative pain; however, it takes time to set up and administer.
Nurses evaluated patient-care tasks with fentanyl iontophoretic transdermal system and/or morphine intravenous patient-controlled analgesia in two phase IIIb studies (n = 1305) using a nurse ease-of-care questionnaire. A responder for time-efficiency and convenience responded with one of the top three positive choices on all items; for satisfaction, a responder chose one of the top two positive choices on both items. Data were collected between March 2004 and April 2005.
In both studies, greater proportions of nurses were responders for fentanyl iontophoretic transdermal system than for morphine intravenous patient-controlled analgesia, respectively, for time-efficiency [total hip replacement surgery, 80.9% (250/309) vs. 57.7% (172/298), P < 0.001; abdominal/pelvic surgery, 84.8% (162/191) vs. 57.7% (113/196), P < 0.001], convenience [total hip replacement surgery, 85.5% (271/317) vs. 64.1% (191/298), P < 0.001; abdominal/pelvic surgery, 89.2% (166/186) vs. 62.8% (123/196), P < 0.001], and satisfaction [total hip replacement surgery, 66.6% (247/371) vs. 33.3% (108/324), P < 0.001; abdominal/pelvic surgery, 67.4% (155/230) vs. 38.2% (84/220), P < 0.001]. Higher proportions of nurses favoured fentanyl iontophoretic transdermal system than morphine intravenous patient-controlled analgesia in both studies (P < 0.001).
The fentanyl iontophoretic transdermal system appears to be simpler, easier to use, and more satisfactory for nurses than morphine intravenous patient-controlled analgesia.
比较芬太尼离子导入透皮系统与吗啡静脉自控镇痛对术后患者护理的时间效率和便利性的影响。
吗啡静脉自控镇痛有效地用于管理术后疼痛;然而,其设置和给药需要时间。
在两项IIIb期研究(n = 1305)中,护士使用护士护理简易性问卷对芬太尼离子导入透皮系统和/或吗啡静脉自控镇痛的患者护理任务进行评估。对于时间效率和便利性,应答者从所有项目的前三个积极选择中选择其一;对于满意度,应答者从两个项目的前两个积极选择中选择其一。数据收集于2004年3月至2005年4月之间。
在两项研究中,对于时间效率[全髋关节置换手术,80.9%(250/309)对57.7%(172/298),P < 0.001;腹部/盆腔手术,84.8%(162/191)对57.7%(113/196),P < 0.001]、便利性[全髋关节置换手术,85.5%(271/317)对64.1%(191/298),P < 0.001;腹部/盆腔手术,89.2%(166/186)对62.8%(123/196),P < 0.001]和满意度[全髋关节置换手术,66.6%(247/371)对33.3%(108/324),P < 0.001;腹部/盆腔手术,67.4%(155/230)对38.2%(84/220),P < 0.001],与吗啡静脉自控镇痛相比,护士中认为芬太尼离子导入透皮系统符合要求的比例更高。在两项研究中,相比于吗啡静脉自控镇痛,更多比例的护士更倾向于芬太尼离子导入透皮系统(P < 0.001)。
与吗啡静脉自控镇痛相比,芬太尼离子导入透皮系统对护士而言似乎更简单、更易于使用且更令人满意。