Fujitsu Laboratories of Europe Ltd., Hayes UB4 8FE, UK.
IEEE Trans Biomed Eng. 2009 Oct;56(10):2404-12. doi: 10.1109/TBME.2009.2022548. Epub 2009 May 19.
The bidomain equations are frequently used to model the propagation of cardiac action potentials across cardiac tissue. At the whole organ level, the size of the computational mesh required makes their solution a significant computational challenge. As the accuracy of the numerical solution cannot be compromised, efficiency of the solution technique is important to ensure that the results of the simulation can be obtained in a reasonable time while still encapsulating the complexities of the system. In an attempt to increase efficiency of the solver, the bidomain equations are often decoupled into one parabolic equation that is computationally very cheap to solve and an elliptic equation that is much more expensive to solve. In this study, the performance of this uncoupled solution method is compared with an alternative strategy in which the bidomain equations are solved as a coupled system. This seems counterintuitive as the alternative method requires the solution of a much larger linear system at each time step. However, in tests on two 3-D rabbit ventricle benchmarks, it is shown that the coupled method is up to 80% faster than the conventional uncoupled method-and that parallel performance is better for the larger coupled problem.
双域方程常用于模拟心脏动作电位在心脏组织中的传播。在整个器官水平上,所需的计算网格的大小使得它们的解成为一个重大的计算挑战。由于数值解的准确性不能妥协,因此解算技术的效率对于确保在合理的时间内获得模拟结果而同时仍包含系统的复杂性是很重要的。为了提高求解器的效率,双域方程通常被解耦为一个抛物型方程,该方程的计算成本非常低廉,而一个椭圆型方程的计算成本则要昂贵得多。在这项研究中,将这种非耦合的解决方案方法的性能与另一种策略进行了比较,在该策略中,将双域方程作为一个耦合系统进行求解。这似乎违反直觉,因为替代方法要求在每个时间步都要解决一个更大的线性系统。但是,在对两个 3-D 兔心室基准测试的测试中,表明耦合方法比传统的非耦合方法快 80%,并且对于更大的耦合问题,并行性能更好。