White Stephen H
Department of Physiology and Biophysics, and Center for Biomembrane Systems, University of California, Irvine, California 92697, USA.
Nature. 2009 May 21;459(7245):344-6. doi: 10.1038/nature08142.
The first atomic-resolution structure of a membrane protein was solved in 1985. Twenty-four years and more than 180 unique structures later, what have we have learned? An examination of the atomic details of several diverse membrane proteins reveals some remarkable biophysical features and suggests that we can expect to achieve much more in the decades to come.
1985年解析出了首个膜蛋白的原子分辨率结构。24年后，已有180多个独特结构，我们学到了什么？对几种不同膜蛋白的原子细节进行研究后发现了一些显著的生物物理特征，并表明在未来几十年我们有望取得更多成果。
