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肝硬化患者肝细胞癌的腹腔镜肝切除术

Laparoscopic hepatectomy for hepatocellular carcinoma in cirrhotic patients.

作者信息

Kaneko Hironori, Tsuchiya Masaru, Otsuka Yuichiro, Yajima Satoshi, Minagawa Teruaki, Watanabe Masashi, Tamura Akira

机构信息

Department of Surgery (Omori), Toho University School of Medicine, 6-11-1 Omorinishi, Ota-ku, Tokyo, 143-0015, Japan.

出版信息

J Hepatobiliary Pancreat Surg. 2009;16(4):433-8. doi: 10.1007/s00534-009-0123-5. Epub 2009 May 21.

Abstract

INTRODUCTION

We have used laparoscopic hepatectomy as a surgical treatment for HCC in patients with cirrhosis. We describe the indications, evaluate invasiveness and analyze the outcomes of laparoscopic hepatectomy.

METHODS AND RESULTS

With respect to operative method, laparoscopic hepatectomy involving either partial hepatectomy or left lateral sectionectomy is a less invasive procedure in patients with cirrhosis than conventional hepatectomy. Among our laparoscopic hepatectomy cases, operative time was shorter and bleeding was less in recent, as compared to earlier, cases. Furthermore, laparoscopic hepatectomy was less invasive than conventional hepatectomy, as determined by the E-PASS scoring system. Patients also recovered more quickly, which resulted in shorter hospital stays even for patients with cirrhosis. Both the 5-year survival rate and the rate of survival without recurrence of HCC were nearly identical to those of open conventional hepatectomy.

CONCLUSION

These findings indicate that laparoscopic hepatectomy avoids the disadvantages of standard hepatectomy for HCC in properly selected patients with cirrhosis and that its minimal invasiveness improves patients' quality of life.

摘要

引言

我们已将腹腔镜肝切除术作为肝硬化患者肝癌的手术治疗方法。我们描述其适应证,评估其侵袭性并分析腹腔镜肝切除术的结果。

方法与结果

关于手术方法,与传统肝切除术相比,腹腔镜肝切除术(包括部分肝切除术或左外侧段切除术)对肝硬化患者的侵袭性较小。在我们的腹腔镜肝切除术病例中,与早期病例相比,近期病例的手术时间更短,出血更少。此外,根据E-PASS评分系统,腹腔镜肝切除术的侵袭性低于传统肝切除术。患者恢复也更快,这使得即使是肝硬化患者的住院时间也更短。肝癌的5年生存率和无复发生存率与开放性传统肝切除术几乎相同。

结论

这些发现表明,在适当选择的肝硬化患者中,腹腔镜肝切除术避免了标准肝切除术治疗肝癌的缺点,其微创性改善了患者的生活质量。

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