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[口服非诺特罗对哮喘儿童的治疗效果评估]

[Evaluation of the therapeutic effectiveness of orally administered fenoterol in asthmatic children].

作者信息

Tafuro B, Soffiati F, Rubin R, Pierfederici P, Dall'Agnola A

机构信息

Divisione di Pediatria, USSL 28, Legnago, Verona, Italia.

出版信息

Pediatr Med Chir. 1991 May-Jun;13(3):261-4.

PMID:1945993
Abstract

In a single blind controlled trial we evaluated the effectiveness of fenoterol, administrated by oral route, in 14 pediatric patients, suffering from allergic asthma. The study was designed through three cycles of therapy: the first with fenoterol (0.25 mg/kg), the second with placebo and the third with the active drug again. The duration of each period was of one month and every two weeks a clinical and spirometric evaluation were performed. Positive data with statistically significant differences for the spirometric parameters were found together with a good safety and tolerability.

摘要

在一项单盲对照试验中,我们评估了口服非诺特罗对14名过敏性哮喘儿科患者的疗效。该研究设计了三个治疗周期:第一个周期使用非诺特罗(0.25毫克/千克),第二个周期使用安慰剂,第三个周期再次使用活性药物。每个周期持续一个月,每两周进行一次临床和肺功能评估。结果发现,肺功能参数的阳性数据具有统计学显著差异,同时安全性和耐受性良好。

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