Peterson Ryan C, Patel Lisa, Cubert Kenneth, Gulati Amitabh
Weill Medical College, Cornell University, New York, NY, USA.
Pain Physician. 2009 May-Jun;12(3):629-32.
While intractable itching may be rarely associated with postherpetic neuralgia, it can have catastrophic complications if present.
We highlight a severe case of postherpetic itching in a 10-year-old male with Fanconi's and aplastic anemia, refractory to conventional treatments and requiring intravenous sedation.
Our use of 3 sequential stellate ganglion blocks with 5.5 mL of 0.25% bupivacaine provided significant improvement of the symptoms for 4 months after the last procedure.
Although further evaluation is needed, we feel that novel use of sympathetic blockade may provide treatment for intractable itching. Highlighted is the possible influence of the sympathetic system in the pathophysiology of postherpetic itch.
The use of serial stellate ganglion blocks may be a treatment option for patients with intractable itching and postherpertic neuralgia of the neck and arm region. This technique may lead to more permanent solutions such as pulse radiofrequency lesion or chemical neurolysis of sympathetic ganglions for postherpetic itch.
虽然顽固性瘙痒可能很少与带状疱疹后神经痛相关,但如果出现,可能会引发灾难性并发症。
我们重点介绍了一名10岁患有范可尼贫血和再生障碍性贫血的男性患者的严重带状疱疹后瘙痒病例,该病例对传统治疗无效,需要静脉镇静。
我们使用0.25%布比卡因5.5毫升连续进行3次星状神经节阻滞,在最后一次手术后4个月内症状得到显著改善。
虽然需要进一步评估,但我们认为交感神经阻滞的新应用可能为顽固性瘙痒提供治疗方法。强调了交感神经系统在带状疱疹后瘙痒病理生理学中的可能影响。
连续星状神经节阻滞的应用可能是颈部和手臂区域顽固性瘙痒和带状疱疹后神经痛患者的一种治疗选择。这种技术可能会带来更持久的解决方案,如脉冲射频损伤或交感神经节化学神经溶解术来治疗带状疱疹后瘙痒。