Hassan Shahzeb, Cohen Philip R
Dermatology, Northwestern University Feinberg School of Medicine, Chicago, USA.
Dermatology, San Diego Family Dermatology, San Diego, USA.
Cureus. 2019 Sep 16;11(9):e5665. doi: 10.7759/cureus.5665.
Postherpetic pruritus is an uncommon adverse sequela of Varicella zoster infection. It can present with or without prior postherpetic neuralgia. A 57-year-old woman who developed persistent postherpetic pruritus following a Varicella zoster infection, affecting the skin between her right thoracic fifth to eighth dermatomes is described; she did not have postherpetic neuralgia. Her condition did not improve with systemic antiviral or gabapentin treatment; however, nine years later, she exhibited significant relief after two months of acyclovir 800 mg five times daily. In summary, postherpetic pruritus is a potential complication that can occur alone or in combination with postherpetic neuralgia. Some patients with postherpetic pruritus have a treatment-refractory disease. However, other patients respond to gabapentin; yet, long-term interventions may be necessary for persistent pruritus. Our patient's pruritus significantly improved after restarting systemic antiviral therapy.
带状疱疹后瘙痒是水痘带状疱疹感染罕见的不良后遗症。它可伴有或不伴有先前的带状疱疹后神经痛。本文描述了一名57岁女性，在水痘带状疱疹感染后出现持续性带状疱疹后瘙痒，累及右侧胸5至胸8皮节之间的皮肤；她没有带状疱疹后神经痛。她的病情在接受全身性抗病毒治疗或加巴喷丁治疗后并未改善；然而，9年后，她在每天5次服用800毫克阿昔洛韦两个月后症状明显缓解。总之，带状疱疹后瘙痒是一种可能单独发生或与带状疱疹后神经痛并发的潜在并发症。一些带状疱疹后瘙痒患者患有难治性疾病。然而，其他患者对加巴喷丁有反应；不过，对于持续性瘙痒可能需要长期干预。我们的患者在重新开始全身性抗病毒治疗后瘙痒症状明显改善。
