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普瑞巴林治疗疱疹后瘙痒:一例报告

Pregabalin for postherpetic itch: a case report.

作者信息

Shimada Nobuhiro, Niwa Yasunori, Hotta Kunihisa, Igarashi Takashi, Takeuchi Mamoru

机构信息

Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.

出版信息

JA Clin Rep. 2020 Mar 23;6(1):24. doi: 10.1186/s40981-020-00330-x.

DOI:10.1186/s40981-020-00330-x
PMID:32206971
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7090110/
Abstract

BACKGROUND

Postherpetic itch has not commonly received attention as a complication of herpes zoster because pain predominates over itch in most patients with herpes zoster. Most cases of postherpetic itch are mild; however, cases of severe postherpetic itch reducing quality of life are rare.

CASE PRESENTATION

A 52-year-old woman complained of severe itch in her left pinna and cheek 1 month after the first onset of herpes zoster at the same site. Owing to her scratching, she developed ulcers on her left pinna and cheek. Pregabalin was prescribed, and the itch subsided immediately, with the ulcers disappearing within 1 month.

DISCUSSION

Severe itch was thought to be caused by neural injury from herpes zoster. Pregabalin may be a useful treatment option for neuropathic itch induced by herpes zoster.

摘要

背景

疱疹后瘙痒作为带状疱疹的一种并发症,通常未受到关注,因为在大多数带状疱疹患者中,疼痛比瘙痒更为突出。大多数疱疹后瘙痒病例症状较轻;然而,严重影响生活质量的疱疹后瘙痒病例较为罕见。

病例介绍

一名52岁女性在同一部位首次发生带状疱疹1个月后,主诉左耳廓和脸颊严重瘙痒。由于搔抓,她的左耳廓和脸颊出现了溃疡。给予普瑞巴林治疗后,瘙痒立即缓解,溃疡在1个月内消失。

讨论

严重瘙痒被认为是由带状疱疹引起的神经损伤所致。普瑞巴林可能是治疗带状疱疹引起的神经性瘙痒的一种有效选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dec/7090110/e0cd43857fd9/40981_2020_330_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dec/7090110/e0cd43857fd9/40981_2020_330_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dec/7090110/e0cd43857fd9/40981_2020_330_Fig1_HTML.jpg

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