Saladini Monica, Lazzari Sandra, Pignedoli Francesca, Rosa Roberto, Spagnolo Ferdinando, Ferrari Erika
Department of Chemistry, University of Modena and Reggio Emilia, Modena, Italy.
Plant Foods Hum Nutr. 2009 Sep;64(3):224-9. doi: 10.1007/s11130-009-0122-3.
Turmeric extracts, among which curcumin and bis-demethoxycurcumin, are by far known for their therapeutic activities. In this study we propose easy and low cost synthetic pathways in order to obtain glucosyl-curcuminoids, safe and water soluble potential drugs and dyes, which may be implied in different fields ranging from pharmacology to food chemistry. The complete (1)H and (13)C NMR characterization of naturally occurring curcumin, bis-demethoxycurcumin and new synthetic glucosyl-curcuminoids is reported.
姜黄提取物,其中包括姜黄素和双去甲氧基姜黄素,迄今为止因其治疗活性而闻名。在本研究中,我们提出了简便且低成本的合成途径,以获得葡糖基姜黄素类化合物,它们是安全且水溶性的潜在药物和染料,可能应用于从药理学到食品化学等不同领域。本文报道了天然存在的姜黄素、双去甲氧基姜黄素以及新合成的葡糖基姜黄素类化合物的完整氢谱(¹H NMR)和碳谱(¹³C NMR)表征。