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临时与非临时经皮冠状动脉介入治疗的预测因素及结果

Predictors and outcomes of ad hoc versus non-ad hoc percutaneous coronary interventions.

作者信息

Hannan Edward L, Samadashvili Zaza, Walford Gary, Holmes David R, Jacobs Alice, Sharma Samin, Katz Stanley, King Spencer B

机构信息

School of Public Health, University at Albany, State University of New York, Albany, New York 12144, USA.

出版信息

JACC Cardiovasc Interv. 2009 Apr;2(4):350-6. doi: 10.1016/j.jcin.2009.01.006.

Abstract

OBJECTIVES

Our aim was to compare longer-term outcomes for ad hoc percutaneous coronary intervention (PCI) and non-ad hoc PCI.

BACKGROUND

Ad hoc PCIs, whereby PCI is performed immediately after cardiac catheterization, has become the most common way of performing PCI. However, no studies have compared longer-term outcomes for ad hoc and non-ad hoc PCIs.

METHODS

A total of 46,565 New York State patients who underwent PCI in nonfederal New York State hospitals between January 1, 2003 and June 30, 2005 were followed through December 31, 2005, and in-hospital and longer-term outcomes were compared for ad hoc and non-ad hoc PCI patients after adjusting for differences in pre-procedural risk factors.

RESULTS

There was no difference in risk-adjusted in-hospital mortality (adjusted ad hoc/non-ad hoc odds ratio: 0.82, 95% confidence interval [CI]: 0.55 to 1.22). Ad hoc PCI patients had significantly lower 36-month mortality (adjusted hazard ratio [HR]: 0.76, 95% CI: 0.69 to 0.85, p < 0.0001). Ad hoc PCI patients had significantly higher 36-month subsequent revascularization (adjusted HR: 1.11, 95% CI: 1.01 to 1.21, p = 0.03), but after excluding subsequent PCIs that occurred within 30 days of the index PCI in another vessel, the difference was no longer significant (adjusted HR: 1.03, 95% CI: 0.95 to 1.12, p = 0.43).

CONCLUSIONS

On average, lower-risk patients undergo ad hoc PCI, and after risk-adjustment for differences in patient mix, ad hoc PCI patients have lower 3-year mortality rates.

摘要

目的

我们的目的是比较临时经皮冠状动脉介入治疗(PCI)和非临时PCI的长期结果。

背景

临时PCI即在心脏导管插入术后立即进行PCI,已成为进行PCI最常见的方式。然而,尚无研究比较临时和非临时PCI的长期结果。

方法

对2003年1月1日至2005年6月30日期间在纽约州非联邦医院接受PCI的46565例纽约州患者进行随访,直至2005年12月31日,并在对术前危险因素差异进行调整后,比较临时和非临时PCI患者的院内及长期结果。

结果

风险调整后的院内死亡率无差异(调整后的临时/非临时比值比:0.82,95%置信区间[CI]:0.55至1.22)。临时PCI患者的36个月死亡率显著较低(调整后的风险比[HR]:0.76,95%CI:0.69至0.85,p<0.0001)。临时PCI患者的36个月后续血运重建率显著较高(调整后的HR:1.11,95%CI:1.01至1.21,p=0.03),但在排除首次PCI后30天内在另一血管发生的后续PCI后,差异不再显著(调整后的HR:1.03,95%CI:0.95至1.12,p=0.43)。

结论

平均而言,低风险患者接受临时PCI,在对患者构成差异进行风险调整后,临时PCI患者的3年死亡率较低。

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