认知储备
Cognitive reserve.
作者信息
Stern Yaakov
机构信息
Cognitive Neuroscience Division of the Taub Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, United States.
出版信息
Neuropsychologia. 2009 Aug;47(10):2015-28. doi: 10.1016/j.neuropsychologia.2009.03.004. Epub 2009 Mar 13.
Abstract
The concept of reserve has been proposed to account for the disjunction between the degree of brain damage and its clinical outcome. This paper attempts to produce a coherent theoretical account the reserve in general and of cognitive reserve in particular. It reviews epidemiologic data supporting the concept of cognitive reserve, with a particular focus of its implications for aging and dementia. It then focuses on methodologic issues that are important when attempting to elucidate the neural underpinnings of cognitive reserve using imaging studies, and reviews some of our group's work in order to demonstrate these issues.
摘要
储备这一概念已被提出，用以解释脑损伤程度与其临床结果之间的脱节。本文试图对储备，尤其是认知储备，给出一个连贯的理论阐释。文章回顾了支持认知储备概念的流行病学数据，特别关注其对衰老和痴呆症的影响。接着，文章聚焦于在试图通过影像学研究阐明认知储备的神经基础时至关重要的方法学问题，并回顾了我们团队的一些工作以说明这些问题。
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