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挪威养老院患者抑郁的 12 个月随访研究。

A 12 months follow-up study of depression among nursing-home patients in Norway.

机构信息

Norwegian Centre for Dementia Research, Department of Geriatric Medicine, Ullevaal University Hospital, N 0407, Oslo, Norway.

出版信息

J Affect Disord. 2010 Jan;120(1-3):141-8. doi: 10.1016/j.jad.2009.04.028.

Abstract

BACKGROUND

Depression is common in nursing-home patients and is often of chronic nature.

AIMS

To examine the prevalence, incidence and the persistence rates of clinically significant depressive symptoms, and their risk factors among nursing-home patients.

DESIGN

A 12 months follow-up study.

METHODS

A sample of 902 randomly selected nursing-home patients was assessed using the Cornell Scale, the Clinical Dementia Rating Scale, the Self-Maintenance Scale and a measurement of physical health. Information was collected from the patients' records. Clinically significant depression was defined as 8+ on the Cornell Scale.

RESULTS

At 12 months 231 had died, and depression was together with higher age, worse physical health, poor function in activities of daily living, higher CDR score and cancer a significant predictor of death (0.03). The prevalence of depression was 21.2% at baseline and follow-up, incidence rate was 14.9% and persistence rate was 44.8%. Predictors of depression at 12 months were: high Cornell score at baseline (p<0.001), a shorter stay in a nursing home (0.011) and use of antidepressants (p=0.050); for incident depression: higher Cornell score at baseline (p=0.019), a shorter stay (p=0.002) and higher CDR score (p=0.003); for persistent depression: higher Cornell score at baseline (0.011), use of anxiolytics (p=0.045) and not being married (p=0.037).

CONCLUSION

The incidence and persistence rates of clinical significant depressive symptoms are high in nursing-home patients. A higher score on Cornell Scale at baseline and a shorter stay in a nursing home were predictors for both incidence and persistence of clinically significant depressive symptoms.

摘要

背景

抑郁在养老院患者中很常见,且往往具有慢性特征。

目的

研究养老院患者中临床显著抑郁症状的患病率、发病率和持续率及其危险因素。

设计

一项为期 12 个月的随访研究。

方法

采用康奈尔量表、临床痴呆评定量表、自我维持量表和身体健康测量对 902 名随机选择的养老院患者进行评估。信息从患者的记录中收集。临床显著抑郁定义为康奈尔量表得分为 8+。

结果

12 个月时,231 人死亡,抑郁与较高的年龄、较差的身体健康状况、日常生活活动功能较差、较高的 CDR 评分和癌症一起是死亡的显著预测因素(0.03)。基线和随访时的抑郁患病率为 21.2%,发病率为 14.9%,持续率为 44.8%。12 个月时抑郁的预测因素为:基线时康奈尔评分较高(p<0.001)、在养老院的停留时间较短(0.011)和使用抗抑郁药(p=0.050);对于新发抑郁:基线时康奈尔评分较高(p=0.019)、停留时间较短(p=0.002)和 CDR 评分较高(p=0.003);对于持续性抑郁:基线时康奈尔评分较高(0.011)、使用抗焦虑药(p=0.045)和未婚(p=0.037)。

结论

养老院患者临床显著抑郁症状的发病率和持续率较高。基线时康奈尔量表评分较高和在养老院停留时间较短是临床显著抑郁症状发病和持续的预测因素。

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