Vertes V, Tobias L, Galvin S
Department of Special Programs, Mt. Sinai Medical Center of Cleveland, Ohio.
Prim Care. 1991 Sep;18(3):471-82.
Sixty million Americans have hypertension, a major cardiovascular risk factor. Its presence accelerates the atherosclerotic process, producing strokes, heart attacks, heart failure, renal failure, and peripheral vascular disease. This article highlights the historical landmarks in the study of this disease from the first documented measurement of blood pressure in 1733, through the most recent pharmacologic approaches to treatment. In addition, the roles of the kidney and the renin-angiotensin-aldosterone system are examined.
六千万美国人患有高血压，这是一个主要的心血管风险因素。高血压的存在会加速动脉粥样硬化进程，引发中风、心脏病发作、心力衰竭、肾衰竭和外周血管疾病。本文重点介绍了从1733年首次有记录的血压测量到最新的药物治疗方法等该疾病研究中的历史里程碑。此外，还探讨了肾脏以及肾素 - 血管紧张素 - 醛固酮系统的作用。
