乳腺具有毛母质生发分化的皮肤型附属器肿瘤：一例报告
Skin-type adnexal tumor with trichoblastic germinative differentiation in the breast: a case report.
作者信息
Gököz Ozay, Presenti Loretta, Gambacorta Giuseppina, Zolfanelli Federica, Tricarico Rossella, Nistri Roberto, Baroni Gianna, Bianchi Simonetta, Massi Daniela
机构信息
Department of Pathology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara, Turkey.
出版信息
Int J Surg Pathol. 2011 Aug;19(4):527-33. doi: 10.1177/1066896909337383. Epub 2009 May 25.
Adnexal tumors with follicular differentiation in the breast parenchyma are rarely encountered. The authors present a unique case arising in a 64-year-old woman, in whom they observed composite differentiation toward follicular germinative cells of the hair follicle with focal areas of outer root sheath differentiation and pilar-type keratinization. The histogenesis of this tumor is analyzed in light of the peculiar pathological, immunohistochemical, and molecular genetic findings.
乳腺实质中具有滤泡分化的附件肿瘤很少见。作者报告了一例发生在一名64岁女性身上的独特病例，他们在该病例中观察到肿瘤向毛囊的滤泡生发细胞呈复合分化，并伴有外根鞘分化和毛干型角化的局灶性区域。根据其独特的病理、免疫组化和分子遗传学发现，对该肿瘤的组织发生进行了分析。
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