He Kun, Li Xueyong, Zhou Junli, Deng Xing-Wang, Zhao Hongyu, Luo Jingchu
College of Life Sciences, Center for Bioinformatics, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871, China.
Bioinformatics. 2009 Jul 15;25(14):1838-40. doi: 10.1093/bioinformatics/btp320. Epub 2009 May 25.
NTAP is designed to analyze ChIP-chip data generated by the NimbleGen tiling array platform and to accomplish various pattern recognition tasks that are useful especially for epigenetic studies. The modular design of NTAP makes the data processing highly customizable. Users can either use NTAP to perform the full process of NimbleGen tiling array data analysis, or choose post-processing modules in NTAP to analyze pre-processed epigenetic data generated by other platforms. The output of NTAP can be saved in standard GFF format files and visualized in GBrowse.
The source code of NTAP is freely available at http://ntap.cbi.pku.edu.cn/. It is implemented in Perl and R and can be used on Linux, Mac and Windows platforms.
NTAP旨在分析由NimbleGen平铺阵列平台生成的ChIP芯片数据，并完成各种模式识别任务，这些任务对表观遗传学研究特别有用。NTAP的模块化设计使数据处理具有高度可定制性。用户既可以使用NTAP执行NimbleGen平铺阵列数据分析的全过程，也可以在NTAP中选择后处理模块来分析由其他平台生成的预处理表观遗传学数据。NTAP的输出可以保存为标准GFF格式文件，并在GBrowse中可视化。
NTAP的源代码可在http://ntap.cbi.pku.edu.cn/免费获取。它用Perl和R实现，可在Linux、Mac和Windows平台上使用。
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