Suppr超能文献

椎间盘内固醇在椎间盘源性下腰痛治疗中的作用。

The role of intradiscal steroids in the treatment of discogenic low back pain.

机构信息

Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, USA.

出版信息

Curr Rev Musculoskelet Med. 2008 Jun;1(2):103-7. doi: 10.1007/s12178-007-9015-y.

Abstract

LBP is one of the most common reasons for visiting a doctor and is the most common cause of disability under age 45.Amongst a variety of etiologies, internal disc disruption (IDD) has been postulated as an important cause of low back pain. Treating discogenic low back pain continues to be a challenge to physicians. Inflammation, either from direct chemical irritation or secondary to an autoimmune response to the nucleus pulposus has been implicated as the primary pain source. Both steroids and non-steroidal anti-inflammatory drugs have partial effectiveness in treating pain associated with inflammation. Therefore, the rationale for using intradiscal steroids is to suppress the inflammation within the disc, thereby alleviating the patient's symptoms. The goal of this article is to review the literature regarding the efficacy of intradiscal steroids to treat low back pain of discogenic origin.

摘要

下腰痛是就诊最常见的原因之一,也是 45 岁以下人群残疾的最常见原因。在诸多病因中,椎间盘内部破裂(IDD)被认为是导致下腰痛的重要原因。治疗椎间盘源性下腰痛一直是医生面临的挑战。炎症,无论是来自直接的化学刺激还是继发于对髓核的自身免疫反应,都被认为是主要的疼痛来源。甾体类药物和非甾体类抗炎药在治疗与炎症相关的疼痛方面都有一定的效果。因此,使用椎间盘内类固醇的基本原理是抑制椎间盘内的炎症,从而缓解患者的症状。本文的目的是回顾关于椎间盘内类固醇治疗椎间盘源性下腰痛的疗效的文献。

相似文献

1
The role of intradiscal steroids in the treatment of discogenic low back pain.
Curr Rev Musculoskelet Med. 2008 Jun;1(2):103-7. doi: 10.1007/s12178-007-9015-y.
2
Use of Pulsed Radiofrequency for the Treatment of Discogenic Back Pain: A Narrative Review.
Pain Pract. 2021 Jun;21(5):594-601. doi: 10.1111/papr.12978. Epub 2020 Dec 23.
6
Diagnosis and minimally invasive treatment of lumbar discogenic pain--a review of the literature.
Clin J Pain. 2006 Jun;22(5):468-81. doi: 10.1097/01.ajp.0000208244.33498.05.
9
Percutaneous thermocoagulation intradiscal techniques for discogenic low back pain.
Spine (Phila Pa 1976). 2007 May 1;32(10):1146-54. doi: 10.1097/01.brs.0000261492.55121.93.

引用本文的文献

1
A Proposed Diagnostic and Treatment Algorithm for the Management of Lumbar Discogenic Pain.
J Pain Res. 2025 Jul 1;18:3331-3343. doi: 10.2147/JPR.S522750. eCollection 2025.
2
Effectiveness of intradiscal steroid injection for spinal stenosis: a retrospective cohort study in South Korea.
Asian Spine J. 2025 Aug;19(4):545-552. doi: 10.31616/asj.2024.0513. Epub 2025 Apr 22.
3
Does intradiscal steroid injection accelerate the histological degeneration of the human disc?
Osteoporos Sarcopenia. 2024 Sep;10(3):108-113. doi: 10.1016/j.afos.2024.06.001. Epub 2024 Jul 2.
5
Optimization of a rat lumbar IVD degeneration model for low back pain.
JOR Spine. 2020 Jun 22;3(2):e1092. doi: 10.1002/jsp2.1092. eCollection 2020 Jun.

本文引用的文献

1
Diagnosis and minimally invasive treatment of lumbar discogenic pain--a review of the literature.
Clin J Pain. 2006 Jun;22(5):468-81. doi: 10.1097/01.ajp.0000208244.33498.05.
2
The effect of spinal steroid injections for degenerative disc disease.
Spine J. 2004 Sep-Oct;4(5):495-505. doi: 10.1016/j.spinee.2004.03.024.
3
The use of intradiscal steroid therapy for lumbar spinal discogenic pain: a randomized controlled trial.
Spine (Phila Pa 1976). 2004 Apr 15;29(8):833-6; discussion 837. doi: 10.1097/00007632-200404150-00002.
7
Histologic changes in the intervertebral disc after intradiscal injections of methylprednisolone acetate in rabbits.
Spine (Phila Pa 1976). 1997 Jan 15;22(2):127-31; discussion 132. doi: 10.1097/00007632-199701150-00001.
8
Intradiscal corticosteroids in the treatment of lumbar and cervical disc problems.
Spine (Phila Pa 1976). 1980 Jul-Aug;5(4):385-9. doi: 10.1097/00007632-198007000-00013.
9
The pathophysiology of degenerative disease of the lumbar spine.
Orthop Clin North Am. 1983 Jul;14(3):491-504.
10
Synopsis: workshop on idiopathic low-back pain.
Spine (Phila Pa 1976). 1982 Mar-Apr;7(2):141-9. doi: 10.1097/00007632-198203000-00009.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验