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[对生甜椒的严重1型过敏]

[Severe type 1-allergy to raw bell pepper].

作者信息

Rüger R D, Wagner S, Simon J C, Treudler R

机构信息

Klinik für Dermatologie, Venerologie und Allgergologie, Universitätsklinikum Leipzig A.ö.R., Philipp-Rosenthal-Strasse 23-25, 04103 Leipzig.

出版信息

Hautarzt. 2010 Apr;61(4):339-42. doi: 10.1007/s00105-009-1776-3.

DOI:10.1007/s00105-009-1776-3
PMID:19475361
Abstract

We report on a patient with rare anaphylaxis after ingestion of raw bell pepper. A complex cluster of sensitization including grass and birch pointed out a possible pollen-associated food allergy. We suggest that the severe reaction is due to cross-reactivity towards Bet v 1. Western blot showed binding of the patient's serum to an 11 kDa protein, which has not been described yet and might be a new allergenic structure of the bell pepper plant or a fragment of the Bet v 1-homologous bell pepper protein.

摘要

我们报告了一例食用生甜椒后发生罕见过敏反应的患者。包括草和桦树在内的复杂致敏簇表明可能存在花粉相关的食物过敏。我们认为严重反应是由于对Bet v 1的交叉反应所致。蛋白质印迹显示患者血清与一种11 kDa蛋白质结合,该蛋白质尚未见报道,可能是甜椒植物的一种新的致敏结构或Bet v 1同源甜椒蛋白的片段。

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[Severe type 1-allergy to raw bell pepper].[对生甜椒的严重1型过敏]
Hautarzt. 2010 Apr;61(4):339-42. doi: 10.1007/s00105-009-1776-3.
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Effects of gastrointestinal digestion and heating on the allergenicity of the kiwi allergens Act d 1, actinidin, and Act d 2, a thaumatin-like protein.胃肠道消化和加热对猕猴桃过敏原Act d 1(肌动蛋白)、肌动蛋白酶和Act d 2(类奇异果甜蛋白)致敏性的影响。
Mol Nutr Food Res. 2008 Oct;52(10):1130-9. doi: 10.1002/mnfr.200700167.
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Genetic and environmental factors affecting allergen-related gene expression in apple fruit (Malus domestica L. Borkh).
影响苹果果实(苹果属家苹果L. Borkh.)中过敏原相关基因表达的遗传和环境因素。
J Agric Food Chem. 2008 Aug 13;56(15):6707-16. doi: 10.1021/jf800813d. Epub 2008 Jul 11.
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Soy allergy in perspective.大豆过敏的相关情况。
Curr Opin Allergy Clin Immunol. 2008 Jun;8(3):270-5. doi: 10.1097/ACI.0b013e3282ffb157.
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A structural basis for food allergy: the role of cross-reactivity.食物过敏的结构基础:交叉反应性的作用。
Curr Opin Allergy Clin Immunol. 2008 Feb;8(1):82-6. doi: 10.1097/ACI.0b013e3282f4177e.
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Impact of occupational and inhalant allergy on rhinitis-specific quality of life in employees of bell pepper greenhouses in the Netherlands.职业性和吸入性过敏对荷兰甜椒温室员工鼻炎特异性生活质量的影响。
Ann Allergy Asthma Immunol. 2006 Jan;96(1):92-7. doi: 10.1016/S1081-1206(10)61046-0.
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9
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J Allergy Clin Immunol. 2004 Jul;114(1):127-30. doi: 10.1016/j.jaci.2004.04.033.