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阿姆斯特丹人群中B19微小病毒血清流行率的研究。

Population-based study on the seroprevalence of parvovirus B19 in Amsterdam.

作者信息

van Rijckevorsel G G C, Sonder G J B, Schim van der Loeff M F, van den Hoek J A R

机构信息

Public Health Service Amsterdam, Department of Infectious Diseases, Amsterdam, The Netherlands.

出版信息

J Med Virol. 2009 Jul;81(7):1305-9. doi: 10.1002/jmv.21528.

DOI:10.1002/jmv.21528
PMID:19475607
Abstract

A study was undertaken to estimate the seroprevalence of parvovirus B19 infection in the general adult population of Amsterdam, The Netherlands. To our knowledge this is the first study testing parvovirus B19 in a random sample of the Dutch adult population. The study was a cross-sectional survey, and the study sample was stratified by age and ethnicity, with deliberate oversampling of minority ethnic groups. Serum samples obtained from 1,323 residents in 2004 were tested for antibodies to parvovirus B19. Basic demographic data (gender, age, country of birth, and number of children) were also available. Sixty-two percent of the participants were seropositive; corrected for the oversampling the estimated prevalence in the Amsterdam adult population was 61%. No specific predictors or risk groups for seropositivity were identified. In our urban adult study population no positive correlation with increasing neither age, nor significant differences between age groups were found. These results imply that almost 40% of the adult Amsterdam population is susceptible to infection. J. Med. Virol. 81:1305-1309, 2009. (c) 2009 Wiley-Liss, Inc.

摘要

开展了一项研究,以估计荷兰阿姆斯特丹普通成年人群中B19细小病毒感染的血清阳性率。据我们所知,这是首次在荷兰成年人群随机样本中检测B19细小病毒的研究。该研究为横断面调查,研究样本按年龄和种族分层,少数族裔群体有意进行了过度抽样。对2004年从1323名居民中获得的血清样本检测了B19细小病毒抗体。还获取了基本人口统计学数据(性别、年龄、出生国家和子女数量)。62%的参与者血清呈阳性;校正过度抽样后,阿姆斯特丹成年人群的估计患病率为61%。未确定血清阳性的特定预测因素或风险组。在我们的城市成年研究人群中,未发现血清阳性与年龄增长呈正相关,也未发现年龄组之间存在显著差异。这些结果表明,近40%的阿姆斯特丹成年人群易受感染。《医学病毒学杂志》81:1305 - 1309,2009年。(c) 2009威利 - 利斯公司。

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