Fraggetta F, Pepe P, Giunta M L, Aragona F
Department of Pathology, Cannizzaro Hospital, Catania, Italy.
Pathologica. 2008 Dec;100(6):482-4.
Malignant tumours of the prostate other than carcinomas are rare. One such malignant tumours arising from the specialised stromal tissue of the prostate is stromal prostatic sarcoma (namely low-grade and high-grade). Herein, we report the clinico-pathological features of a high grade stromal sarcoma of the prostate occurring in a 65-year-old man who presented for urinary obstructive symptoms. The clinical picture suggested a benign prostatic hyperplasia, and surgery consisting in a transcapsular adenomectomy was performed. Following a pathological diagnosis of high grade prostatic stromal sarcoma, a radical cystoprostatectomy and bilateral pelvic node dissection was performed showing residual high grade stromal sarcoma of the prostate and incidental in situ urothelial carcinoma of the bladder. No further medical treatments were planned. One year after surgery the patient is well with no evidence of local disease or distant metastases.
除癌以外的前列腺恶性肿瘤很少见。一种起源于前列腺特殊间质组织的恶性肿瘤是前列腺间质肉瘤(即低级别和高级别)。在此,我们报告一名65岁男性发生的高级别前列腺间质肉瘤的临床病理特征,该患者因尿路梗阻症状就诊。临床表现提示为良性前列腺增生,遂行经包膜腺瘤切除术。在病理诊断为高级别前列腺间质肉瘤后,进行了根治性膀胱前列腺切除术和双侧盆腔淋巴结清扫术,结果显示残留高级别前列腺间质肉瘤以及膀胱偶然原位尿路上皮癌。未计划进一步的医学治疗。术后一年,患者情况良好,无局部疾病或远处转移的迹象。