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千里光对耐抗生素葡萄球菌的抗菌活性及化学成分

Antimicrobial activity and chemical composition of Senecio sandrasicus on antibiotic resistant staphylococci.

作者信息

Ugur Aysel, Sarac Nurdan, Duru M Emin

机构信息

Department of Biology, Faculty of Science and Arts, Mugla University, 48121 Kotekli-Mugla, Turkey.

出版信息

Nat Prod Commun. 2009 Apr;4(4):579-84.

PMID:19476010
Abstract

The antimicrobial activity of hexane, chloroform, ethyl acetate and ethanol extracts of the aerial parts of S. sandrasicus P.H.Davis (Asteraceae), endemic to Sandras mountain (Turkey), were determined. The antimicrobial activity of the extracts on microorganisms including multi-resistant staphylococci were evaluated using the disc diffusion method. The strains of multi-resistant staphylococci and the other standart bacteria were inhibited by some extracts. The volatile organic compouds of S. sandrasicus was determined by Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS). The major compounds of hexane extract were aromadendrene oxide 2 (13.3%), spathulenol (12.5%) and beta-caryophylene (11.8%), respectively.

摘要

对原产于土耳其桑德拉斯山的菊科植物桑德拉斯千里光地上部分的己烷、氯仿、乙酸乙酯和乙醇提取物的抗菌活性进行了测定。采用纸片扩散法评估提取物对包括多重耐药葡萄球菌在内的微生物的抗菌活性。一些提取物对多重耐药葡萄球菌菌株和其他标准细菌具有抑制作用。通过气相色谱(GC)和气相色谱-质谱联用(GC-MS)测定了桑德拉斯千里光的挥发性有机化合物。己烷提取物的主要化合物分别为氧化香树烯2(13.3%)、匙叶桉油烯醇(12.5%)和β-石竹烯(11.8%)。

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