Department of Biology, Faculty of Arts and Sciences, Mugla University, 48121 Kotekli-Mugla, Turkey.
Acta Pharm. 2009 Dec;59(4):463-72. doi: 10.2478/v10007-009-0036-5.
Hexane, chloroform, ethyl acetate and ethanolic extracts of the aerial parts of Centaurea austro-anatolica Hub.-Mor. (Asteraceae) were evaluated against microorganisms, including multiresistant bacteria, using a paper disc diffusion method. The chloroform extract exhibited significant antibacterial activity toward all bacteria tested. The chemical composition of the chloroform extract was determined by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The major compounds of the extract were caryophyllene oxide (21.32 %), spathulenol (10.86 %), n-tricosanol (9.58 %) and geranyl isovalerate (8.71 %).
用纸片扩散法评估了白花千里光（菊科）地上部分的正己烷、氯仿、乙酸乙酯和乙醇提取物对微生物（包括多药耐药菌）的抑制作用。氯仿提取物对所有测试的细菌均显示出显著的抗菌活性。通过气相色谱（GC）和气相色谱-质谱联用（GC-MS）确定了氯仿提取物的化学成分。提取物的主要化合物为石竹烯氧化物（21.32%）、斯巴醇（10.86%）、正二十烷醇（9.58%）和香叶基异戊酸酯（8.71%）。
