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以口腔黏膜病变为表现的系统性红斑狼疮——病例报告

Systemic lupus erythematosus presenting with oral mucosal lesions--a case report.

作者信息

Ramakrishna Y, Reddy J Sharada

机构信息

Dept. of Pedodontics & Preventive Dentistry, K.D Dental College and Hospital, Mathura, Uttar Pradesh, India.

出版信息

J Clin Pediatr Dent. 2009 Spring;33(3):255-8. doi: 10.17796/jcpd.33.3.h7m84x4450x03768.

Abstract

Systemic Lupus Erythematosus (SLE) is an autoimmune rheumatic disease, principally affecting women during child bearing years and is characterized by the presence of auto antibodies against a variety of auto antigens such as double-stranded DNA, intracellular ribonuclear proteins and membrane phospholipids. The presentation of lupus erythematosus ranges from a skin rash unaccompanied by extracutaneous stigmata to a rapidly progressive lethal multiorgan disease. A wide spectrum of oral mucosal lesions is found in the cutaneous and systemic forms of lupus erythematosus. We report a 11-year-old female child with classical features of Systemic Lupus Erythematosus associated with oral mucosal lesions.

摘要

系统性红斑狼疮(SLE)是一种自身免疫性风湿性疾病,主要影响育龄期女性,其特征是存在针对多种自身抗原的自身抗体,如双链DNA、细胞内核糖核蛋白和膜磷脂。红斑狼疮的表现范围从无皮肤外体征的皮疹到迅速进展的致命性多器官疾病。在皮肤型和系统性红斑狼疮中都发现了广泛的口腔黏膜病变。我们报告了一名11岁女童,具有系统性红斑狼疮的典型特征并伴有口腔黏膜病变。

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