Seaton Kimberly A, Slack Kelley J, Sipes Walter A, Bowie Kendra E
University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Aviat Space Environ Med. 2009 May;80(5 Suppl):A62-5. doi: 10.3357/asem.br09.2009.
This report is one of a series on the Flight Analog Project, which is designed to lay the groundwork for a standard bed rest protocol. The Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) is a self-administered battery of tests used on the International Space Station for evaluating cognitive functioning. Here, WinSCAT was used to assess cognitive functioning during extended head-down bed rest.
There were 13 subjects who participated in 60 or 90 d of head-down bed rest and took WinSCAT during the pre-bed rest phase, the in-bed rest phase, and the post-bed rest (reconditioning) phase of study participation.
After adjusting for individual baseline performance, 12 off-nominal scores were observed out of 351 total observations during bed rest and 7 of 180 during reconditioning. No evidence was found for systematic changes in off-nominal incidence as time in bed rest progressed, or during the reconditioning period.
Cognitive functioning does not appear to be adversely affected by long-duration head-down bed rest. Individual differences in underlying cognitive ability and motivation level are likely explanations for the current findings.
本报告是飞行模拟项目系列报告之一,该项目旨在为标准卧床休息方案奠定基础。适用于Windows系统的航天飞行认知评估工具(WinSCAT)是一套用于国际空间站评估认知功能的自陈式测试。在此,WinSCAT用于评估长时间头低位卧床休息期间的认知功能。
有13名受试者参与了60天或90天的头低位卧床休息,并在研究参与的卧床休息前阶段、卧床休息阶段和卧床休息后(恢复)阶段进行了WinSCAT测试。
在对个体基线表现进行调整后,卧床休息期间351次总观察中有12次异常分数,恢复期间180次观察中有7次。未发现随着卧床休息时间的延长或恢复期间异常发生率有系统性变化的证据。
长时间头低位卧床休息似乎不会对认知功能产生不利影响。潜在认知能力和动机水平的个体差异可能是当前研究结果的原因。