Falade Adegoke G, Ige Olusoji M, Yusuf Bidemi O, Onadeko Modupe O, Onadeko Babatunde O
Department of Pediatrics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
J Natl Med Assoc. 2009 May;101(5):414-8. doi: 10.1016/s0027-9684(15)30925-1.
The increase in prevalence of asthma and other allergic diatheses has rarely been documented in the developing sub-Saharan countries. We assessed time trends in symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema among children in Ibadan, Nigeria, with cross-sectional data from 2 International Study of Asthma and Allergies in Childhood questionnaire-based surveys conducted 7 years apart in 1995 and in 2001-2002. The prevalence of current wheeze increased nonsignificantly in the 6- to 7-year age group (4.8%-5.5%) and significantly in the 13- to 14-year age group (10.7%-13.0%) (p = .249 and p = .005, respectively). The 12-month prevalence of allergic rhinoconjuctivitis decreased insignificantly in the 6- to 7-year age group (p = .833) but significantly in the 13- to 14-year age group (p = .001), while the diagnosis of atopic eczema decreased in both age groups. The current findings suggest that the symptoms of asthma have only increased significantly in the Nigerian adolescents.
在撒哈拉以南的发展中国家，哮喘和其他过敏性素质的患病率增加情况鲜有记录。我们利用1995年和2001 - 2002年相隔7年进行的2次基于儿童哮喘和过敏国际研究问卷的横断面调查数据，评估了尼日利亚伊巴丹儿童哮喘、过敏性鼻结膜炎和特应性皮炎的症状随时间的变化趋势。6至7岁年龄组当前喘息患病率无显著增加（4.8% - 5.5%），而13至14岁年龄组显著增加（10.7% - 13.0%）（分别为p = 0.249和p = 0.005）。6至7岁年龄组过敏性鼻结膜炎的12个月患病率无显著下降（p = 0.833），但13至14岁年龄组显著下降（p = 0.001），而两个年龄组特应性皮炎的诊断率均下降。目前的研究结果表明，哮喘症状仅在尼日利亚青少年中显著增加。
