Department of Paediatrics, College of Medicine, University of Ibadan, Ibadan, Department of Paediatrics, University College Hospital, Ibadan, Nigeria.
Kwame Nkrumah University of Science and Technology, Kumasi, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Int J Tuberc Lung Dis. 2023 Dec 1;27(12):925-930. doi: 10.5588/ijtld.23.0138.
Phases I and III of the International Study of Asthma and Allergies in Childhood (ISAAC) documented increased asthma symptoms among Nigerian 13-14-year old adolescents. We investigated the trend further using the Global Asthma Network (GAN) surveillance. Using ISAAC methodology, GAN Phase I data on symptoms and risk factors for asthma and asthma management were obtained from February to July 2018. There were 2,897 adolescents from 23 secondary schools. For current wheeze, there was an absolute prevalence fall per decade of -1.4 with -1 standard error (SE) in 16 years from 2002 (ISAAC Phase III) to 2018 (GAN Phase I). This pattern was evident for prevalence of reported asthma ever, severe asthma symptoms and night cough with ≥1 SE. During the 23-year interval between ISAAC Phase I and GAN Phase I, there was a fall (≥1 SE) in the absolute prevalence of reported asthma ever, severe asthma symptoms and night cough, except for severe asthma symptoms (-0.2 SE). Respectively 36% and 43% of symptomatic adolescents purchased and used salbutamol and prednisolone. The prevalence and severity of asthma symptoms remain high among adolescents in Ibadan. This could be mitigated by improved access to affordable and effective asthma treatments.
国际儿童哮喘和过敏研究（ISAAC）的 I 期和 III 期研究记录了尼日利亚 13-14 岁青少年哮喘症状的增加。我们使用全球哮喘网络（GAN）监测进一步调查了这一趋势。使用 ISAAC 方法，从 2018 年 2 月至 7 月获得了 GAN 阶段 I 关于哮喘症状和危险因素以及哮喘管理的数据。共有来自 23 所中学的 2897 名青少年。对于当前喘息，从 2002 年（ISAAC III 期）到 2018 年（GAN 期 I）的 16 年中，每十年的绝对患病率下降了 1.4，标准差（SE）为 1.4。对于报告的哮喘史、严重哮喘症状和夜间咳嗽≥1 SE，这种模式明显存在。在 ISAAC 第一阶段和 GAN 第一阶段之间的 23 年间隔内，报告的哮喘史、严重哮喘症状和夜间咳嗽的绝对患病率均有所下降（≥1 SE），但严重哮喘症状除外（-0.2 SE）。分别有 36%和 43%的有症状青少年购买并使用沙丁胺醇和泼尼松龙。伊巴丹青少年的哮喘症状发生率和严重程度仍然很高。通过改善获得负担得起和有效的哮喘治疗的机会，可以减轻这种情况。
