伴有异常染色体异常的急性淋巴细胞白血病：t(3;9) (p21;p13)，del(10p12) [13]
Acute lymphoblastic leukaemia with unusual chromosomal abnormality: t(3;9) (p21;p13), del(10p12) [13].
作者信息
Dhingra Bhavna, Bhargava Rahul, Mishra Pravas
机构信息
Department of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India.
出版信息
Leuk Res. 2009 Dec;33(12):e221-3. doi: 10.1016/j.leukres.2009.04.029. Epub 2009 May 23.
We report a case of pre-B acute lymphoblastic leukaemia with an unusual translocation between chromosome 3 and 9, with del(10p12) [13]. The diagnosis at presentation was made by the morphology, cytochemistry and immunophenotyping. Cytogenetic analysis was also done at presentation. To the best of our knowledge and after literature search this appears to be a rare cytogenetic abnormality in ALL.
我们报告1例前体B细胞急性淋巴细胞白血病，其3号和9号染色体之间存在异常易位，并伴有10号染色体短臂12区缺失[13]。初诊时通过形态学、细胞化学和免疫表型分析做出诊断。初诊时也进行了细胞遗传学分析。据我们所知并经文献检索，这似乎是急性淋巴细胞白血病中一种罕见的细胞遗传学异常。
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