Høgdall E V, Høgdall C K, Clemmensen I, Nørgaard-Pedersen B, Loft A G
Department of Clinical Biochemistry, Statens Seruminstitut, Glostrup, Denmark.
Scand J Clin Lab Invest. 1991 Sep;51(5):411-5. doi: 10.3109/00365519109091634.
The concentration of the newly discovered protein tetranectin has been measured in different fetal and maternal compartments. In amniotic fluid a significant, positive correlation between the tetranectin concentration and gestational age was found (a mean of 0.2 mg l-1 at week 14 to a mean of 0.5 mg l-1 at week 21). In maternal serum a slight negative correlation was found between tetranectin concentration and gestational week (a mean of 6.17 mg l-1 at week 14 to a mean of 5.79 mg l-1 at week 21). In-term cord blood collected at delivery a mean level of 6.0 mg l-1 was found, and no difference was found between arterial- and venous-blood tetranectin concentration. In fetal serum the overall mean level was 2.6 mg l-1 and a significant positive correlation between tetranectin concentration and gestational age was found. The mean level was 1.1 mg l-1 in fetal cerebrospinal fluid and no correlation to gestational age was found. Fetal tetranectin may, therefore, be correlated to fetal maturation.
已对新发现的蛋白腱生蛋白在不同胎儿和母体腔室中的浓度进行了测量。在羊水中，发现腱生蛋白浓度与胎龄之间存在显著的正相关（第14周时平均为0.2mg/L，到第21周时平均为0.5mg/L）。在母体血清中，腱生蛋白浓度与孕周之间存在轻微的负相关（第14周时平均为6.17mg/L，到第21周时平均为5.79mg/L）。分娩时采集的足月脐带血中腱生蛋白平均水平为6.0mg/L，动脉血和静脉血中的腱生蛋白浓度没有差异。胎儿血清中的总体平均水平为2.6mg/L，且发现腱生蛋白浓度与胎龄之间存在显著的正相关。胎儿脑脊液中的平均水平为1.1mg/L，且未发现与胎龄相关。因此，胎儿腱生蛋白可能与胎儿成熟有关。
