El-Sherbiny Walid, Saber Walid, Askalany Ahmed N, El-Daly Ashraf, Sleem Ahmed A Abde-aziz
Department of Obstetrics and Gynecology, Cairo University Faculty of Medicine, Cairo, Egypt.
Int J Gynaecol Obstet. 2009 Sep;106(3):213-5. doi: 10.1016/j.ijgo.2009.04.016. Epub 2009 May 27.
To assess the effect of intraperitoneal instillation of lidocaine on postoperative pain after minor gynecological laparoscopic surgery.
A prospective, double-blind, placebo-controlled clinical trial of 75 patients undergoing gynecological laparoscopy randomized to receive intraperitoneal instillation of either 120 mg of lidocaine (n=60) or normal saline (n=15) at the end of surgery. Postoperative pain was evaluated by Wong-Baker Faces Pain Rating Scale (WBFS) score at 15 minutes and at 1, 2, 4, 12, and 24 hours postoperatively.
The WBFS score was lower for the lidocaine group than for the control group at 1, 2, and 4 hours after surgery (P=0.023). There was no difference in WBFS scores between the 2 groups at 15 minutes (P=0.46), 12 hours (P=0.13), and 24 hours (P=0.07) after surgery.
Intraperitoneal instillation of lidocaine was effective in reducing postoperative pain after minor gynecological laparoscopic procedures.
评估腹腔内注入利多卡因对妇科小腹腔镜手术后疼痛的影响。
一项前瞻性、双盲、安慰剂对照临床试验,75例接受妇科腹腔镜手术的患者在手术结束时随机接受腹腔内注入120毫克利多卡因(n = 60)或生理盐水(n = 15)。术后疼痛通过面部表情疼痛评分量表(WBFS)在术后15分钟以及术后1、2、4、12和24小时进行评估。
利多卡因组术后1、2和4小时的WBFS评分低于对照组(P = 0.023);术后15分钟(P = 0.46)、12小时(P = 0.13)和24小时(P = 0.07)两组的WBFS评分无差异(P = 0.07)。
腹腔内注入利多卡因可有效减轻妇科小腹腔镜手术后的疼痛。