超声引导下肾实性肿块细针穿刺活检——组织学与细胞学比较

US-guided fine needle biopsy of solid renal masses--comparison of histology and cytology.

作者信息

Torp-Pedersen S, Juul N, Larsen T, Karstrup S, Sehested M, Glenthøj A

机构信息

Department of Ultrasound, Herlev Hospital, University of Copenhagen, Denmark.

出版信息

Scand J Urol Nephrol Suppl. 1991;137:41-3.

PMID:1947839

Abstract

We report on 134 fine needle biopsies in 127 patients with an ultrasound finding suggesting renal malignancy. Biopsy was performed guided by dynamic ultrasound using an 0.6 mm aspiration needle for cytology and an 0.8 mm Surecut needle for histology. The retrieval rate for cytology was 97.8% compared to 79.1% for histology. Sensitivity for cytology and histology was 89.4% and 70.6%, respectively. The specificity of cytology was 85.4% giving a predictive value of a positive result of 91.6%. Specificity and positive predictive value for histology were both 100%. We conclude that fine needle aspiration biopsy from renal masses in our hands carries too high a false positive rate to be clinically safe. We recommend that fine needle histological biopsy replaces the aspiration biopsy in case of renal masses.

摘要

我们报告了127例超声检查提示肾恶性肿瘤患者的134次细针活检情况。活检在动态超声引导下进行，使用0.6毫米抽吸针进行细胞学检查，0.8毫米Surecut针进行组织学检查。细胞学检查的取材成功率为97.8%，而组织学检查为79.1%。细胞学和组织学的敏感性分别为89.4%和70.6%。细胞学的特异性为85.4%，阳性结果预测值为91.6%。组织学的特异性和阳性预测值均为100%。我们得出结论，在我们手中，对肾肿块进行细针抽吸活检的假阳性率过高，临床安全性不足。我们建议，对于肾肿块，细针组织学活检应取代抽吸活检。